Ayhuasca has played a decisive role both in the origin and preservation of certain religious myths or ideas, as in the development of medicine, among the tribes that have inhabited in the South American jungles, where this "magic" plant grows spontaneously. As soon as it is seen to the current territory of Ecuador, ayahuasca has been used by the Aboriginals of the East and especially the Amazon, a use that is still maintained until our days in some tribes, despite some degree of acculturation. In the region of inter-andina, the use of ayahuasca has been more limited, even in the practice of magic medicine. On the other hand, other hallucinogenic plants, especially some Datura of the Solanaceas family, have been used.