The knowledge and use of hallucinogens, as you know, is quite widely distributed among the American indigenous, and this custom goes back to very remote prehistoric times, perhaps, one before the arrival of man on the American continent. In fact, from North America to Southern regions, you have information on indigenous groups who have employed or still employ certain plants with psychotropic effects to achieve hallucinogenic states of intensity and different characteristics. This article will present my personal observations made on previous years on the use of one hallucinogen (Banisteriopsis Caapi) by the The Tukano Indians from the Uaupès territory, in the Northeast of Columbia.