Ayahuasca is one of the strongest shamanic remedies. The potion brewed from several ethnobotanically important plants of the Amazon region has pervasive physical and astonishing mental effects. Ayahuasca is the basis of culture, creating a culture and preserving institution for many peoples. Ayahuasca is a means of knowledge that shows man his position in the universe and reveals true reality. Applied properly, gives Ayahuasca healing and health, gives personally significant visions and stimulates creative creativity. The authors, proven experts in ethnology, anthropology and pharmacology, show the use of ayahuasa in shamanic rituals. They dive into shamanic-visionary worlds, engage in plants and souls and meet the realities of Amazonian cultures and their artistic works.