The vast resonance of ayahuasca rituals in the cults of the new era corresponds to a reductive approach or assimilation in respect of the culture in which they originated. If the relationship between man and nature is one of the essential and intimate knots of human existence, transversal to the cultures of the world, it can represent a point of contact free from hegemonic settings of human knowledge. But to achieve this result the plan on which the meeting takes place, for spiritual it is, must be accompanied by a real recognition of the symbols and the imaginary that supports it, otherwise it risks becoming a slippery ground on which one tends to mask conflicts and to homologate differences.