Ayahuasca is a psychotropic potion with serotonergic action. The most common botanical sources of ayahuasca are Banisteriopsis caapi and Psychotria viridis, in the Bibliographic Review it was sought to know the biochemical properties, symptoms and signs that Ayahuasca produces corroborating with the effects that it produces when is used as a potion by shamans from the Amazon and being dynamically prepared as a Homeopathic medicine. With this investigation it is possible to compare affirming or denying the empirical indications that the Shamans of our region handle with the different Scientific studies carried out by doctors, anthropologists and psychologists; and see what is the utility that is given in the field of Homeopathy. According to Fericgla, it is useful to induce emotional and spiritual states of a healing, introspective and therapeutic nature. On the other side, it has not been observed that the consumption of Ayahuasca generates psychological or physiological addiction, so it can be stated that it does not represent any danger to Public Health. According to Diego Palma, Di-Methyl-Tryptamine (DMT) is primarily responsible for the psychoactive effects of the brew. Acting at the Thymus and Pineal Gland level. Keywords: Ayahuasca; Yage; Potion; Shaman.