The plants of power are symbols of healing and transpersonal experiences, being recognized as portals that expand consciousness. The research aimed to understand the socio-cultural dimensions of using the ayahuasca drink at the Centro de Unificação Rosa Azul and its association with physical and spiritual health. Data collection took place through participant observation and application of questionnaires and forms. The results showed that the participants present a high understanding of doctrine, plants, ritual, and healing. Plants and drink are considered guides for achieving spiritual evolution and representing physical, mental, and spiritual healing.