In response to the question asked in anthropological circles, ‘do Amazonian shamans really turn into jaguars?’, it seems probable that the answer is yes. They really do turn into jaguars in a similar way that synesthetes really do experience sounds as colours. The reported embodiment of ‘other beings of the cosmos’ by Amazonian ayahuasca shamans appears to refer to deliberate and advanced forms of synesthesia that peak in types of cosmological metamorphosis that give shamans the ability to shift corporality or ‘body image’ and become a variety of dominant ‘qualities of existence’ — that are semantically and sensually associated to animals, plants, radios, and other spirit beings — in order to negotiate spiritual alliances and undertake various shamanic activities, including those related to issues of health and the restoration of wellbeing.