The words “psychedelic renaissance” have been used with increasing frequency in recent years—with good reason. When Psychedelic Medicine was released a decade ago, we were at the beginning of the new professional wave of interest in psychedelics heralding the “psychedelic renaissance” (Sessa, 2012/201 7). The opening of research in the first decade of the 21st century made possible an evaluation of the therapeutic potential of psychedelics, and we are now in the midst of a new understanding of the potential s of psychedelics. The sheer volume of published papers on psychedelics reviewed in the chapters here, and the growing number of research institutions with active psychedelic research programs, attest to this ongoing revolution. It is in the spirit of this objective approach that we present Advances in Psychedelic Medicine. This book expands on the issues addressed in Psychedelic Medicine: Volumes 1 and 2, but rather than an update to those earlier chapters, it addresses new research, topics, and treatment areas that have emerged in the past decade.