The transcendent experience, often described as an ego-dissolving encounter with something greater than one’s self, is cross-cultural and pan-historical. I present a model describing the evolution and function of various evolved modes of transcendence, such as group-directed transcendence, theory of mind (ToM)-evoking transcendence, aesthetic transcendence, and epistemic transcendence. I then discuss the vulnerability of these modes of transcendence to costly exploitation by selfish individuals who activate the transcendent state in others for their own reproductive benefit. In the ensuing section, I discuss the relationship between transcendence and human development across the lifespan, and conclude with some thoughts on the epistemic and ethical utility of transcendence.