Regarding therapeutic potentials, the review by Dr. Stebelska underestimates the potential therapeutic effects of psilocybin/psilocin, suggesting that results from previous human research indicating positive effects could be questioned because volunteers could be prompted by “dishonest” suggestions, that positive effects are “simply ingenuousness,” that research for new treatment options with these compounds are “possibly nonethical,” and that prolonged personality changes “may reflect serious and dangerous ego disorders.”