This paper reports the use of Brugmansia species (Solanaceae) in traditional practices of shamans (curanderos) of Northern Peruvian Andes. The field study permitted the classification of a number of species and/or their hybrids used for both curative and psychotropic activities. There is evidence of a folk systematics in this genus that constitutes a very important phenomenon for its therapeutic-divinatory, phytotherapeutical, and ritual (in initiation and black magic rites) uses. Key Words: Ethnobotany; traditional Andean medicine; Brugmansia.