Ayahuasca is an Amazonian entheogenic brew used for spiritual, medicinal and healing purposes. Over the past three decades the demographic of ayahuasca consumers has changed, rapidly. Once a solely indigenous ritual, ayahuasca consumption has become increasingly popular with new=age shamanic tourists. This has resulted in a multitude of problems for the local and indigenous communities where ayahuasca exists. This theory based dissertation systematically analyses the limited scholarship on the recent appropriation and commodification of ayahuasca and sheds light onto the impact this has had on native communities. Placing the phenomena of ayahuasca appropriation within a wider context of neo-colonialism, indigenous intellectual rights abuses and"bio piracy. Furthermore, using a wide range of this dissertation attempts to explor and examine the motivations for non-natives to consume ayahuasca. Reviewing the importance of the concept of authenticity, this dissertation attempts to conceptualise what drives Westerners out of their affluent homes and into the Amazonian jungles. I conclude my dissertation with reflections on the transcultural sociological future of ayahuasca consumption, alongside recommendations for the protection of the autonomy and rights of indigenous"agents.