This paper will examine the body of folklore of the plant Peganum harmala in the context of the Avestan haoma and the Vedic soma. The evidence for the identification of this plant at the heart of these entheogenic mystery traditions will be gathered from academic theories, etymologies, botanical and astrotheological folklore as well as surviving traces and bioassays of modern recreations of ancient drugs. The horse-riding nomadic Indo-European warriors that ritualized sacred plants preserved the mythological symbolism that stretched from ancient Greece to Tibet. After reappraising and examining soma arguments with the wild rue plant as guru theory, there is an extracted list of potential admixtures that when combined would produce an DMT-laden effect similar to the South American ayahuasca. Keywords: soma, homa, Peganum harmala, entheogens, DMT