This qualitative research implemented in France between 2004 and 2007 is based on 30 in-depth interviews carried out with individuals who consumed hallucinogenic plants or mushrooms at least six times during the year preceding the interview. The interviews were recorded, retranscribed, and an analysis of their content applied for the textual data. The study focuses on drug users and the meanings they attach to their drug use. These meanings involve three different representations of the drugs: “enchanting plants,” “disorientation plants,” and “visionary plants.” Keywords hallucinogenic mushrooms; hallucinogenic plants; qualitative study; contemporary practices; representations of substances; meanings associated with use; poly- drug use