Yage is used throughout the Amazon, particularly in Brazil and Colombia, in addition to Peru. In this paper, I am of course focusing primarily on its usage among indigenous Andean tribes such as the Cashinahua , and particularly on its use in healing and divination rituals. Much has already been written about the use of Yage in Peruvian curanderismo , especially the sort of pseudo-New Age-spiritual tourist cults that seem to have grown around its use in urban areas. In this paper, I am trying to argue three significant points that have not been paid much attention to in the study of Peruvian shamanism. One, that ayahuasca trance is often accompanied by a critical acoustic component involving the use of rattles and whistles. Two, that the shamanic trance may make use of the peculiar lines that line the Peruvian sierra (the ceques ) which link together its many sacred places (huacas.) Third, that yage use is part of an important cosmological culture-complex involving a fascinating ethnoastronomy on the part of its users. And also that the way in which Yage healing is performed has been changing in urban areas.