In Psychedelic Explorations, Claudio talks about his own experience with substances that seem to be, on the one hand, safe enough, and on the other hand, very suitable for undertaking psychedelic therapy with them. These are MMDA, MDMA, ayahuasca, ibogaine, psilocybin, and more. One cannot ignore that the personal experiences described by Claudio, those wonderful sessions transcribed from his psychedelic groups, where marvelous insights and existential gifts of an overwhelming magnitude occur, represent one of the great gifts that this book contributes to the advancement of knowledge. This represents the most luminous aspect of research with psychotropics. Claudio is a shaman recognized by the world of Amazon indigenous Taitas as an equal; likewise, he is someone who has been invested with authority to officiate the ritual reserved for the padrinhos of the Santo Daime; lastly, his rise and referentiality as a researcher from universities such as Berkeley , and professor of the University of California in Santa Cruz, psychiatric doctor, and pioneer researcher in psychopharmacology , is already more than accredited. I dedicate some words to oneirophrenic substances—that is to say, beta-carbol ines and ibogaine. Although regarding the first I have already written enough in my book on ayahuasca, I include in this volume some new texts. I also include as new chapters on ayahuasca the transcription of what was said at the roundtable on ayahuasca and human development at the internationa l conference on ayahuasca in 2014 and the conference on ayahuasca and psychotherapy given online under the auspices of the Open University of Catalonia, which took the unplanned form of a conversation with Mia Fàbregas, who introduced me. I have also included a brief synopsis by Asunta de Hormaechea about her experience taking ayahuasca more than a hundred times with the “Union of the Plant.”