There is an alarming global decline in lncilus alvarius toad populations, the toads who secrete 5-MeO-DMT, because of multiple ecological reasons and the increased interest in toad ‘milking’ for psychedelic experiences. Anya Ermakova, Ph.D. educates the reader on the ecological impacts of these toad populations and provides alternative, synthetic options for psychonauts who would like to use 5-MeO-DMT.