As a psychological anthropologist interested in alternative healing options, I recently traveled to Peru to experience ayahuasca with a shaman I had been corresponding with. Ayahuasca is being used to help treat war veterans and others suffering from PTSD and depression, and its use as a treatment option for addicts is widespread. For thrill-seeking millennials, ayahuasca tourism has also become a trendy activity. As anthropologists know, the set and setting of healing rituals involving altered states of consciousness are of vital importance. My experience took place in an aesthetically pleasing location with shamans who were attentive and nurturing. To protect people who seek out this ancient medicine as a healing modality, regulation may be necessary. Anthropological, psychological, and botanical research can aid in desiring how best to regulate the booming ayahuasca business, creating a safe option for those desiring alternative mental health treatment.