An examination of field data on ayahuasca has shown that one cannot examine the use of hallucinogenic healing in the Peruvian Amazon region without a complementary analysis of witchcraft beliefs and activities. This paper has attempted to remedy the great neglect in the use of hallucinogens such as Banisteriopsis to bewitch. Using data on ayahuasca and bewitching activity, a test was made of Kennedy's hypothesis that relates witchcraft beliefs to paranoid delusional states: the major premises linking these two phenomenahas been confirmed by the data. It is hoped that testing of this hypothesis with future field data will point up some important areas of hallucinogenic use in witchcraft activity throughout the Peruvian rain forest region.