Despite almost six decades having passed since Szára’s first study, we appear to be no closer to a definitive explanation for DMT’s astonishing psychoactive effects. It’s quite tempting to assume that the strangely characteristic DMT-­‐like experiences that so many users report, from playful giggling elves to grotesque alien “pro-­‐bono proctologists”, can be explained in terms of modern cultural memes that propagate through underground psychedelic literature, archival Terence McKenna lectures and, most recently, through the internet. However, the few surviving trip reports from these early DMT studies perhaps suggest that things are a little more complicated than that and therein lay their importance. The authors are currently performing a detailed (and long overdue) quantitative phenomenological analysis of Strassman’s original ‘bedside notes’ and such carefully recorded trip reports will likely form the primary data source in future research, although psychedelic researchers should be prepared to enter the DMT realm themselves with the aim of answering specific questions and performing experiments. After all, if you want a tiger’s cub, you must go into the tiger’s cave. DMT is unique amongst the classical psychedelics in not only being very short acting, but also not exhibiting a tolerance effect with repeated use (Strassman et al., 1996). As such, using the same technology developed for maintaining a stable brain concentration of anaesthetic drugs during surgery, it would be feasible to administer DMT by precisely regulated continuous intravenous infusion, permitting the explorer an extended, and theoretically indefinite, sojourn in the DMT reality. Although a well-­prepared strong ayahuasca brew might achieve a crudely comparable effect, standardisation of the dose is much more difficult and the concentration of DMT in the brain will fluctuate based on a range of pharmacokinetic and metabolic factors. A well-­‐designed continuous IV protocol could account for these factors, allowing the brain DMT concentration to be kept stable or manipulated to gradually move the explorer deeper and deeper into the DMT space. This approach might give the brave voyagers enough time to orient themselves, get their intellective tools in order and cast their nets far out into the “dark ocean of mind” in the hope of bringing back the message that DMT has been trying to convey since Szára first dipped his toes in the water almost 60 years ago. If ever there was a time, it’s now. Ahoy, shipmates! Ahoy!