Through the selected examples presented here, the extraordinary richness of the ethno-psycho-pharmacological field of investigation can be realised. Even though the traditional use of hallucinogens is not recent, it is to the great merit of people like Albert Hofmann that they have greatly contributed to its rediscovery. Is this not exactly the kind of effects that shamans are looking for when choosing a hallucinogen from their natural environment - a true religious experience? The more we learn about the ethnopharmacology of natural hallucinogens, the more we may realize how LSD is similar to these alkaloids.