Four indole bases have been found to occur in the seeds and pods of P. peregrina (L.) Benth. and P. macrocarpa Benth. The pods contain N,N-dimethyltryptamine, and the seeds contain bufotenine, bufotenine oxide and N, N-dimethyltryptamine oxide. In addition, a 5-hydroxyindole base of unknown structure was found in P. macrocarpa seeds. The identification of these compounds was accomplished by isolation through paper chromatography, and comparison with authentic samples involving Rf data, ultraviolet spectra and fluorescence analysis. The synthesis of these two oxides, hitherto unknown as components of plant or animal metabolism, is described.