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The role of 5-HT2A, 5-HT2C and mGlu2 receptors in the behavioral effects of tryptamine hallucinogens N,N-dimethyltryptamine and N,N-diisopropyltryptamine in rats and mice

journal Article

2015

Theresa M., Carbonaro Amy J., Eshleman Michael J., Forster Kejun, Cheng Kenner C., Rice Michael B., Gatch

DOI: 10.1007/s00213-014-3658-3 Share

Web link: link.springer.com/10.1007/s...

Pages: 275 - 284

Abstract

Rationale: Serotonin 5-HT2A and 5-HT2C receptors are thought to be the primary pharmacological mechanisms for serotonin-mediated hallucinogenic drugs, but recently there has been interest in metabotropic glutamate (mGluR2) receptors as contributors to the mechanism of hallucinogens.