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Enzymatic Formation of Psychotomimetic Metabolites from Normally Occurring Compounds


Web link: science.sciencemag.org/content/1...

Pages: 343 - 343

Abstract

An enzyme has been found that N-methylates serotonin and tryptamine to psychotomimetic metabolites, bufotenine and N,N-dimethyltryptamine. This enzyme is highly localized in the rabbit lung and also N-methylates phenylethylamine derivatives such as tyramine, phenylethylamine , mescaline, and dopamine.