The research aimed to investigate the journalistic representations the ayahuasca, through the analysis of materials aired between January 2006 and December 2019, in the Jornal Folha de S. Paulo and in the news website G1. For this, we sought to understand what meanings were produced and put into circulation by such vehicles on the use of the drink. Ayahuasca is a drink used in religious rituals in Brazil and in various other countries the world. Its consumption in religious rituals in the country, began in the indigenous culture of Amazonian tribes and, later, between the decades of 20 and 60, the first religions of ayahuasca appeared, popularly known as Santo Daime, Barquinha and União do Vegetal. We started from the hypothesis that ayahuasca received different types of media framing, sometimes stereotyped, minority and marginalized religious groups, originally from a popular indigenous tradition of the Amazon and that, by using in their religious context a tea with psychoactive properties, often had their practice associated with the use of narcotics and illicit drugs. The main concept of the research will be the representation, used from Jodalet (1989) and Spink (1993). For Jodalet, social representation also serves to guide the action of people in the world, because it qualifies its practical knowledge according to the experiences it itself produces. For the work, we used bibliographic research and content analysis. We use the concept of representation, mediation, stereotype and noticiability criteria. From Bardin (2011), we seek to identify, assess and measure the recurring characteristics of ayahuasca representation modes, highlighting the repetition and frequency of the use of terms and nomenclatures on the object. Keywords: Ayahuasca. Stereotype. Mediation. Journalistic discourse. Representation.