In Colombia, the expansion of the yagecero field over the past 20 years is linked to the urbanization and elitization of yage consumption (a recognized practice of indigenous origin) promoted by the appearance of an urban spiritual therapeutic market led by indigenous and non-indigenous specialists known as “taitas yageceros.” This opening of the traditional field is profoundly permeated by the effects of the introduction of multiculturalism as a state policy in Colombia with the promulgation of the Constitution of 1991. The constitutional recognition of indigenous cultural difference opened a new legal section of differential rights for these populations. The expansion of yage consumption is given within this context of the legitimations of indigenous identities and of the recognition of their cultural manifestations. This is why, in Colombia, the legitimacy – and the legality – of yage consumption is given mainly in terms of a therapeutic practice belonging to the cultural sphere of certain indigenous traditions, in contrast to countries such as Brazil, where it is recognized for its religious nature of mestizo origin (Labate, 2004). The appearance of new specialists or “new yagecero taitas” in a kind of interface between the yagecero tradition of the Amazon and the ritual innovations aimed at the urban public has, over the past 15 years, markedly transformed the yagecero field, together with its operational dynamics and logic. Thus, in light of the allegations of sexual assault by Taita Orlando Gaitán, we would like to explore the recent evolution of this interface in order to propose a number of clues that can help us understand the risks and threats of the current yagecero field. This work is based on my research as an expert advisor for the Prosecutor’s Office for this case, and it is supported by the data from a previous study (Caicedo, 2015), as well as new information gathered in interviews carried out with people close to the CPPB, its followers and former followers, between 2015 and 2016. It should be made clear that the judicial inquiry is still underway and to date there has been no official judgment on the case. I will therefore not delve too deeply into direct information from the allegations.