Drawing together this overview, if there is an overarching theme here in this special issue, it is that psychedelics – with the right set and setting – can give rise to a sense of deep connection with Nature, which may extend as far as interspecies communication or the formulation and maintenance of an animist worldview, subsequent healing, and ultimately ecocentric activism as opposed to egocentric action. Coming full circle then to my own animistic dialogue with Nature under the inluence of a psychedelic plant all those years ago, if there is a metaphor in my own metamorphosis it’s that we as a species must change or be changed if we and other species on this planet are to survive. The starting point for that transformation into becoming a part of, rather than apart from, our ecosystem is our own individual consciousness. EDITORIAL. Ecopsychology and the psychedelic experience David Luke Preparing the Gaia connection: An ecological exposition ofpsychedelic literature 1954-1963 Robert Dickins Returning to Wirikuta: The Huichol and their sense of place David Lawlor Interspecies communication in the Western Amazon: Music as a form of conversation between plants and people Christina Callicott Psychedelic top knots Dale Pendell Snake medicine: How animism heals Robert Tindall Entheogenic rituals, shamanism and green psychology Ralph Metzner The responsible use of entheogens in the context of bioregionalism Eleonora Molnar Shamanism and psychedelics: A biogenetic structuralist paradigm of ecopsychology Michael Winkelman From ecopsychology to transpersonal ecosophy: Shamanism, psychedelics, and transpersonal psychology. An autobiographical reflection Mark Schroll