The number of locations with evidence of isolated peoples and the frequency of sometimes violent incidents with neighbouring populations have intensified significantly during the last decade. The veteran sertanista José Carlos Meirelles has called it ‘The Decade of Contact’ (Shepard, 2017), a period which demands serious political attention, adequate resources, effective strategies and close collaboration between the Peruvian and Brazilian governments to ensure the protection of isolated peoples on both sides of the border. The success of the emergency contact carried out by Funai in 2014 with the Xinane people, with no casualties to infectious diseases, is evidence of the high competence and experience of the team. DACI interventions in Peru with the Mashco-Piro people to avoid escalating conflicts with neighbouring communities are also proof of the success of this proactive policy when taken in time.