This article discusses concepts and practices of healing in Brazilian religions which have in common the use of a psychoactive beverage mainly known by the names of Daime, Vegetal and Ayahuasca. These religions are elaborated from the same set of cultural traditions which nonetheless unfolds in different ways. All of them originate in the Brazilian Amazon region and in some cases, these processes expand to other parts of Brazil and abroad. We compare here the ways in which the healing is experienced and explained in these religions, emphasizing the representations concerning this beverage used in all of them. The case of these religions points to the complexity of the relation between both scientific and religious medicines.