Because of the process of fast acculturation in the North-West Amazonia, this system of knowledge is not static, but in continous transformation, simultaneously to the progress of transcultural contacts between the ethnic groups and the western civilization. In this way, particularly in the urban context, some of these plants have been replaced by new products of Western culture (parfums, gasoline, etc.). Different authors studied this argument through the direct analysis of different socio-cultural contexts: PINKLEY (38); RIVIER & LINDGREN (44); McKENNA,LUNA & TOWERS (25); LUNA (23). The aim of the present communication is to confronte these different sources and to establish some possible interpretative keys, from a pharmacodynamic point of view, to elaborate future research.