The effect of Daime varies according to the preparation technique (Bongiorno de Pfirter, 1984) doses and type of mixture, and possibly also the circumstances during which it is consumed (prayers, singing and dancing). The leaves of the plants are macerated, boiled and bottled. Previously it has been estimated that a 200 ml portion of Daime contains 30 mg of harmine, 10 mg of tetrahydroharmine and 25 mg of DMT (Bongiorno de Ptirter et al. 1984). In our sample of an equal amount we found considerably more active substances: 298 mg of harmine; 106 mg of DMT; and 278 mg of tetrahydroharmine. The old Amazon Indian herbal potion which is served by the expanding religious cult contains pharmacologically active hallucinogenic principles.